Next-generation vaccines for Covid-19 should aim to induce an immune response against ‘replication proteins’, essential for the very earliest stages of the viral cycle, concludes new research carried out by University College London (UCL) scientists.
By designing vaccines that activate immune memory cells, known as T cells, to attack infected cells expressing this part of the virus’s internal machinery, it may be possible to eliminate DOI: 10.1038/s41586-021-04186-8
This research was funded by the NIHR and UKRI’s UK Coronavirus Immunology Consortium.
The COVIDsortium is supported by funding donated by individuals, charitable Trusts, and corporations, with institutional support from Barts Health NHS Trust and Royal Free NHS Foundation Trust, in partnership with University College London and Queen Mary University London.
“Replication Proteins” – New Target for Next-Generation COVID-19 Vaccines